Hormones & endocrine

Adrenocorticotropic hormone

Typical unit pmol/L

The pituitary hormone that tells the adrenal glands to make cortisol.

What it is

Adrenocorticotropic hormone links the brain's pituitary to the adrenal glands. It varies strongly through the day and needs careful sample handling, so it is a specialist test.

Why it matters

ACTH is interpreted together with cortisol to work out where an adrenal-axis problem sits; it is not meaningful on its own.

This guide is educational only and cannot diagnose you. Discuss results, especially anything outside your laboratory’s reference interval, or that does not match how you feel, with a GP or other appropriately qualified clinician.

How it affects the body

ACTH drives cortisol production, part of the body's stress and energy regulation.

For athletes

Anabolic steroid use suppresses this axis; interpreting ACTH during or after a cycle is specialist territory.

Related tests

No published panels currently list this marker.

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